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Publications

Journal covers
2016 - Selective Protein Hyperpolarizati

Viennet T, Viegas A, Kuepper A, Arens S, Gelev V, Petrov O, Grossmann TN, Heise H, Etzkorn M, 2016,

 

Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization,

 

Angewandte Chemie International Edition, 55, 10746 –10750

DOI: https://doi.org/10.1002/anie.201603205

2019 - Molecular Architecture of a Netwo

Viegas A, M.Yin D, Borggräfe J, Viennet T, Falke M, Schmitz A, Famulok M, Etzkorn M,

2019,

 

Molecular Architecture of a Network of Potential Intracellular EGFR Modulators: ARNO, CaM, Phospholipids, and the Juxtamembrane Segment,

 

Structure, 28 (1), 54-62.e5

DOI: https://doi.org/10.1016/j.str.2019.11.001

2021_Local_Deuteration_Cover.jpg

Dubey A,  Stoyanov N,  Viennet  T, Chhabra S,  Elter S,  Borggräfe J, Viegas  A, Nowak  RP, Burdziev  N, Petrov  O, Fischer ES, Etzkorn M, Gelev  V, Arthanari H,

2021,

Local Deuteration Enables NMR Observation of Methyl Groups in Proteins from Eukaryotic and Cell‐Free Expression Systems,

 

Angewandte Chemie International Edition, 60, 13783-13787,

DOI: https://doi.org/10.1002/anie.202016070

The FEBS Journal - 2023 -  - Issue Information.png

Borggräfe J., Gertzen C. G. W., Viegas A., Gohlke H., Etzkorn M., 2022,

The architecture of the 10-23 DNAzyme and its implications for DNA-mediated catalysis

 

The FEBS Journal, 290, 8, 1937-2200

DOI: https://doi.org/10.1111/febs.16698

Papers in international scientific journals
2022

24.

Borggräfe J., Gertzen C. G. W., Viegas A., Gohlke H., Etzkorn M., 2023, The architecture of the 10-23 DNAzyme and its implications for DNA-mediated catalysis, The FEBS Journal, 290, 8, 1937-2220.

 

DOI: https://doi.org/10.1111/febs.16698

23.

Gopalswamy M, Kroeger T, Bickel D, Frieg B, Akter S, Schott-Verdugo S, Viegas A, Pauly T, Mayer M, Przibilla J, Reiners J, Nagel-Steger L, Smits SHJ, Groth G, Etzkorn, M, Gohlke H, 2022, Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects, Sci. Rep., 12, 14158.

 

DOI: https://doi.org/10.1038/s41598-022-17913-6

2021

22.

Borggräfe J., Victor J., Rosenbach H., Viegas A., Gertzen C. G. W., Wuebben C., Kovacs H., Gopalswamy M., Riesner D., Steger G., Schiemann O., Gohlke H., Span I., Etzkorn M., 2021, Time-resolved structural analysis of an RNA-cleaving DNA catalyst, Nature. 

 

DOI: https://doi.org/10.1038/s41586-021-04225-4

21.

Dubey A,  Stoyanov N,  Viennet  T, Chhabra S,  Elter S,  Borggräfe J, Viegas  A, Nowak  RP, Burdziev  N, Petrov  O, Fischer ES, Etzkorn M, Gelev  V, Arthanari H, 2021, Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell‐free expression systems, Angewandte Chemie International Edition, 60, 13783-13787

 

DOI: https://doi.org/10.1002/anie.202016070

20.

Duarte M*, Viegas A*, Alves VD, Prates JAM, Ferreira LMA, Najmudin S, Cabrita EJ, Carvalho AL, Fontes CMGA, Bule P, 2021, A dual cohesin–dockerin complex binding mode in Bacteroides cellulosolvens contributes to the size and complexity of its cellulosome, JBC, 296, 100552

 

DOI: https://doi.org/10.1016/j.jbc.2021.100552

2020

19.

Viegas A, Dollinger P, Verma N, Kubiak J, Viennet T, Seidel CAM, Gohlke H, Etzkorn M, Kovacic, Jaeger KE, 2020, Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation, Sci. Rep., 10, 3578.

DOI: https://doi.org/10.1038/s41598-020-60093-4

2019

18.

Ribeiro DO*, Viegas A*, Pires VMR, Silva JM-, Bule P, Chai W, Marcelo F, Fontes CMGA, Cabrita EJ, Palma AS, Carvalho AL, 2019, Molecular basis for the preferential recognition of β1,3‐1,4‐Glucans by the Family 11 Carbohydrate‐Binding Module from Clostridium thermocellum, The FEBS Journal, 287 (13), 2723-2743

DOI: https://doi.org/10.1111/febs.15162

17.

Viegas A, M.Yin D, Borggräfe J, Viennet T, Falke M, Schmitz A, Famulok M, Etzkorn M, 2019, Molecular Architecture of a Network of Potential Intracellular EGFR Modulators: ARNO, CaM, Phospholipids, and the Juxtamembrane Segment, Structure, 28 (1), 54-62.e5

DOI: https://doi.org/10.1016/j.str.2019.11.001

16.

Viennet T, Plümke SB-, Elter S, Viegas A, Fahlke C, Etzkorn M, 2019, Reconstitution and NMR characterization of the ion-channel accessory subunit barttin in detergents and lipid-bilayer nanodiscs, Front. Mol. Biosci. 6 (13)

DOI: https://doi.org/10.3389/fmolb.2019.00013

2016

15.

Brás JL, Pinheiro BA, Cameron K, Cuskin F, Viegas A, Najmudin S, Bule P, Pires VM, Romão MJ, Bayer EA, Spencer HL, Smith S, Gilbert HJ, Alves VD, Carvalho AL, Fontes CM, 2016, Diverse specificity of cellulosome attachment to the bacterial cell surface, Sci Rep. 2016 Dec 7; 6:38292.

DOI: https://doi.org/10.1038/srep38292

14.

Viegas A, Viennet T, Etzkorn M, 2016, The power, pitfalls and potential of the nanodisc system for NMR-based studies, Biological Chemistry, 397 (12), 1335-1354.

DOI: https://doi.org/10.1515/hsz-2016-0224

13.

Viennet T, Viegas A, Kuepper A, Arens S, Gelev V, Petrov O, Grossmann TN, Heise H, Etzkorn M, 2016, Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization, Angewandte Chemie International Edition, 55, 10746 –10750

DOI: https://doi.org/10.1002/anie.201603205

12.

Viegas A, Viennet T, Yu TY, Schumann F, Bermel W, Wagner G, Etzkorn M, 2016, UTOPIA NMR: activating unexploited magnetization using interleaved low-gamma detection, Journal of Biomolecular NMR, 64, 9–15

DOI: https://doi.org/10.1007/s10858-015-0008-7

2014

11.

Elter S, Raschle T, Arens S, Viegas A, Gelev V, Etzkorn M, Wagner G, 2014, The use of amphipols for NMR structural characterization of 7-TM proteins, Journal of Membrane Biology, (247), 957-64.

DOI: https://doi.org/10.1007/s00232-014-9669-5

2013

10.

Pimenta J, Viegas A, Sardinha J, Martins IC, Cabrita EJ, Fontes CMGA, Prates JAM, Pereira  RMLN, 2013, NMR Solution Structure and SRP54M predicted interaction of the N-Terminal sequence (1-30) of the ovine Doppel protein, Peptides, 49, 32-40

DOI: https://doi.org/10.1016/j.peptides.2013.08.013

9.

Pimenta J, Sardinha J, Marques CC, Domingos A, Baptista MC, Barbas JP, Martins IC, Mesquita P, Pessa P, Soares R, Viegas A, Cabrita EJ, Horta AEM, Fontes CMGA, Prates JAM, Pereira RMLN, 2013, Inhibition of ovine in vitro fertilization by anti-Prt antibody. Hypothetical model for Prt/ZP interaction, Reproductive Biology and Endocrinology, 11 (25), 1-11

DOI: https://doi.org/10.1186/1477-7827-11-25

8.

Viegas A, Freire F, Sardinha J, Duarte DF, Carvalho AL, Fontes CMGA, Romão MJ, Macedo AL, Cabrita EJ, 2013, Solution Structure, Dynamics and Binding Studies of a Family 11 Carbohydrate-Binding Module from Clostridium thermocellum (CtCBM11), Biochemical Journal, 451 (2), 289-300

DOI: https://doi.org/10.1042/BJ20120627

2012

7.

Estevão MS, Carvalho LR, Freitas M, Gomes A, Viegas A, Manso J, Fernandes E, Cabrita EJ, Erhardt S and Marques MMB, 2012, Indole based cyclooxygenase-2 inhibitors: synthesis, biological evaluation, docking and NMR screening, European Journal of Medicinal Chemistry, 54, 823-833

DOI: https://doi.org/10.1016/j.ejmech.2012.06.040

6.

Pimenta J, Domingos A, Santos P, Marques CC, Barbas JP, Baptista MC, Horta AEM, Viegas A, Fontes CMGA, Prates JAM and Pereira RMLN, 2012, Is prnt a pseudogene? Identification of ram Prt in testis and ejaculated spermatozoa, Plos One, 7, e42957-e42957

DOI: https://doi.org/10.1371/journal.pone.0042957

5.

Quintal S, Viegas A, Erhardt S, Cabrita EJ and Farrell N, 2012, The interaction of a platinated single strand oligonucleotide and the C-terminal zinc finger of the HIVNCp7, Biochemistry, 51, 1752-1761

DOI: https://doi.org/10.1021/bi201834g

2012

4.

Viegas A, Manso J, Corvo MC, Marques MMB and Cabrita EJ, 2011, Binding of ibuprofen, ketorolac and diclofenac to COX-1 and COX-2 studied by saturation transfer difference NMR, Journal of Medicinal Chemistry, 54, 8555-8562

DOI: https://doi.org/10.1021/jm201090k

3.

Viegas A, Manso J, Nobrega FL, and Cabrita EJ, 2011, Saturation-Transfer Difference (STD) NMR: A simple and fast method for ligand screening and characterization of protein binding, Journal of Chemical Education 88, 990-994

DOI: https://doi.org/10.1021/ed101169t

2009

2

Viegas A, Herrero-Galán E, Oñaderra M, Macedo AL and Bruix M, 2009, Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins, FEBS Journal 276, 2381–2390

DOI: https://doi.org/110.1111/j.1742-4658.2009.06970.x

2008

1.

Viegas A, Brás N, Cerqueira N, Fernandes PA, Prates JAM, Fontes CMGA, Bruix M, Romão MJ, Carvalho AL, Ramos MJ, Macedo AL and Cabrita EJ, 2008, Molecular Determinants of Ligand Specificity in Family 11 Carbohydrate Binding Modules (CBM11): an NMR, X-Ray Crystallography and Computational Chemistry Approach, FEBS Journal, 275, 2524–2535

DOI: https://doi.org/10.1111/j.1742-4658.2008.06401.x

Chapters in Books
2012

2.

Brás, J., Carvalho, A. L., Viegas, A., Najmudin, S., Alves, V. D., Prates, J. A. M., Ferreira, L. M. A., Romão, M. j., Gilbert, H. J.; Fontes, C. M. G. A., 2012, Escherichia coli Expression, Purification, Crystallization, and Structure Determination of Bacterial Cohesin–Dockerin Complexes. In Cellulases, Gilbert, H. J., Ed. Academic Press: Elsevier, Vol. 510, pp. 395.

DOI: https://doi.org/10.1016/B978-0-12-415931-0.00021-5

2010

1.

Viegas, A., Macedo, A. L., Cabrita, E. J., 2012, Ligand-Based Nuclear Magnetic Resonance Screening Techniques. In Ligand-macromolecular interactions in drug discovery: methods and protocols, Roque, A. C. A., Ed. New York: Humana Press: Springer, pp 81

DOI: https://doi.org/10.1007/978-1-60761-244-5_6

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