Aldino Viegas
My main research area is Biomolecular Nuclear Magnetic Resonance and my research interests have been focused on structural biology, particularly on structural determination of proteins and small molecules, protein folding and function, protein/protein and protein/ligand interactions and NMR pulse sequence development.
Research highlights
My Research
The human Norepinephrine Transporter
Molecular basis for ligand recognition of the human norepinephrine transporter
UTOPIA-NMR
Unified time-optimized interleaved acquisition NMR
Cellulosome
A bacterial nanomachine for plant cell wall degradation
Membrane mimetics
Suitable membrane mimicking environment for protein NMR
Ionic Liquids
Tuning protein stability with ionic liquids
Intermolecular interactions
Protein:ligand and protein:protein interactions by NMR
Human Aldehyde Oxidase human
Unravelling drug metabolization
Funding and support
I am very grateful for funding and support from:
- Fundação para a Ciência e a Tecnologia (FCT-MCTES), Portugal, through contract PINFRA/22161/2016-1 and Individual Support Grant 2020.00043.CEECIND, and Research Grants EXPL/BIA-BQM/0011/2021 and 2021.09576.CBM.
- The Applied Molecular Biosciences Unit - UCIBIO which is financed by national funds from FCT (UIDP/04378/2020 and UIDB/04378/2020).
- Rede Nacional de RMN (PTNMR), supported by FCT-MCTES (ROTEIRO/0031/2013- PINFRA/22161/2016) (cofinanced by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC), of which the NMR spectrometers at FCT- NOVA are part.